Epidiolex contains 99% CBD & no other cannabinoids [7or_heQ-yaM]
♦️Epidiolex contains 99% CBD and no other cannabinoids.
♦️OTC CBD oils : add adatives including other cannabinoids to enhance
♦️significantly reduced seizures in LGS, Dravet syndrome, or TSC who failed multiple previous antiseizure medicines in pts older than 1yr.
♦️ contraindicated in people sensitive to sesame oil seeds, pregnancy, suicidal, Hepato-toxic medication‘s
♦️ check LFTs; symptoms of liver problems during treatment with EPIDIOLEX:
♦️Talk to Dr. : Increase asleep, behavioral changes.
anxiety, suicidal thoughts or self-harm, agitation, restlessness, aggression, irritability.
♦️ mostly fecal excretion, minimally in urine
♦️ Half life is 56 to 60 hours
♦️SE: increase in liver enzymes, sleepiness, decreased appetite, diarrhea, fever, vomiting, feeling very tired / weak, rash, sleep problems, infections.
♦️Oral solution: 100 mg/mL
♦️Start: 2.5 mg/kg/dose PO bid x1wk,
Then prn 5 mg/kg/day qwk; titerate slowly. To max : 20 mg/kg/day;
♦️w/ or w/o food;
♦️taper dose gradually to D/C #cbd gummy honolulu #cbd gummy worms for sleep